Response to ?Expression of Endoglin (CD105) in Tumor Blood Vessels?
نویسندگان
چکیده
منابع مشابه
CD105 (endoglin), apoptosis, and stroke.
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متن کاملCD105/smooth muscle actin double immunostaining discriminate between immature and mature tumor blood vessels.
The aim of the study was to demonstrate the value of the double immunostaining for endothelial and perivascular cell to discriminate mature from immature tumor-associated blood vessels in mammary carcinoma. We used the specific endothelial marker CD105 to highlight the activated endothelial cells and antibodies against smooth muscle cell actin (SMA) for perivascular cells, applying Envision Dou...
متن کاملChanges in expression of bile canalicular CD10 and sinusoidal CD105 (endoglin) in peritumoral hepatic tissue.
UNLABELLED AIMS AND BACKGROUND; Hepatic tissues, including bile canaliculi and sinusoids, around primary or metastatic tumors are destructed and regenerate associated with tumor growth, and may show some phenotypic changes. The present study was undertaken to examine the expression of CD10 in bile canaliculi [CD10(BC)] and CD105 (endoglin) along hepatic sinusoids [CD105(HS)] in peritumoral hepa...
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Tumor blood vessels normalized by antiangiogenic therapy may provide improved delivery of chemotherapeutic agents during a window of time but it is unknown how protein expression in tumor vascular endothelial cells changes. We evaluated the distribution of RGD-4C phage, which binds alpha(v)beta(3), alpha(v)beta(5), and alpha(5)beta(1) integrins on tumor blood vessels before and after antiangiog...
متن کاملEndoglin (CD105): a marker of tumor vasculature and potential target for therapy.
Endoglin (CD105) is an accessory protein of the transforming growth factor-beta receptor system expressed on vascular endothelial cells. Mutation of the endoglin gene is associated with hereditary hemorrhagic telangiectasias, or Osler-Weber-Rendu syndrome, and has been studied extensively in the context of this disease. The expression of endoglin is elevated on the endothelial cells of healing ...
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ژورنال
عنوان ژورنال: International Journal of Cancer
سال: 2002
ISSN: 0020-7136,1097-0215
DOI: 10.1002/ijc.10379